医学における生命現象・疾病発症の総合的・統合的メカニズム解明を目指し研究を進めています。

2019年

英文総説

1) Pillai SR, Damaghi M, MARUNAKA Y, Spugnini EP, Fais S, Gillies RJ
Causes, consequences, and therapy of tumors acidosis
Cancer Metastasis Reviews 38(1-2):205-222, 2019

2) Gillies RJ, Pilot C, MARUNAKA Y, Fais S
Targeting acidity in cancer and diabetes
Biochimica et Biophysica Acta Reviews on Cancer 1871(2):273-280, 2019

3) Okada Y, Okada T, Sato-Numata K, Islam MR, Ando-Akatsuka Y, Numata T, Kubo M, Shimizu T, Kurbannazarova RS, MARUNAKA Y, Sabirov RZ
Cell Volume-Activated and -Related Anion Channels in Mammalian Cells: Their Biophysical, Molecular and Pharmacological Properties
Pharmacological Reviews 71(1):49-88, 2019

4) Aoi W, Zou X, Xiao J, MARUNAKA Y
Body Fluid pH Balance in Metabolic Health and Possible Benefits of Dietary Alkaline Foods
eFood (in press)

原著

1) pH balance and lactic acid increase in the vitreous body of diabetes mellitus patients
Mieno H, MARUNAKA Y Y, Inaba T, Kojima K, Yoneda K, Nagata K, Sotozono C
Experimental Eye Research (in press)

2) Inui TA, Yasuda M, Hirano S, Ikeuchi Y, Kogiso H, Inui T, MARUNAKA Y, Nakahari T
Enhancement of ciliary beat amplitude by carbocisteine in ciliated human nasal epithelial cells
Laryngoscope (in press)

3) Konishi T, Shiozaki A, Kosuga T, Kudou M, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, MARUNAKA Y, Otsuji E
LRRC8A expression influences growth of esophageal squamous cell carcinoma
Am J Pathol (in press)

4) Shiozaki A, Yamazato Y, Kosuga T, Kudou M, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, MARUNAKA Y, Otsuji E
Effect of low temperature on the regulation of cell volume after hypotonic shock in gastric cancer cells
Int J Oncol (in press)

5) Inui TA, Murakami K, Yasuda M, Hirano S, Ikeuchi Y, Kogiso H, Hosogi S, Inui T, MARUNAKA Y, Nakahari T
Ciliary beating amplitude controlled by intracellular Cl- and a high rate of CO2 production in ciliated human nasal epithelial cells
Pflügers Archiv – European Journal of Physiology 471(8):1127-1142, 2019

6) Kuwahara A, Kuwahara Y, Kato I, Kawaguchi K, Harata D, Asano S, Toshio Inui, MARUNAKA Y
Xenin-25 induces anion secretion by activating non-cholinergic secretomotor neurons in the rat ileum
Am J Physiol Gastrointest Liver Physiol 316(6):G785-G796, 2019

7) Ikeuchi Y, Kogiso H, Hosogi S, Tanaka S, Shimamoto C, Matsumura H, Inui T, MARUNAKA Y, Nakahari T
Carbocisteine stimulated an increase in ciliary bend angle via a decrease in [Cl-]i in mouse airway cilia
Pflügers Archiv – European Journal of Physiology 471(2):365-380, 2019

8)
Shiozaki A, Ariyoshi Y, Iitaka D, Kosuga T, Shimizu H, Kudou M, Konishi T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, MARUNAKA Y, Ichikawa D, Otsuji E.
Functional analysis and clinical significance of sodium iodide symporter expression in gastric cancer.
Gastric Cancer 22(3):473-485, 2019

国際学会  特別講演、招聘講演、基調講演、教育講演、シンポジウムなど

1) MARUNAKA Y
Plenary Lecture

Actions of flavonoids and natural compounds on ion environments: Its physiological roles
International Workshop on Intelligent Detection of Food and Safety
Jiangsu University
2019.12-13, Zhenjiang, China

2) MARUNAKA Y
Plenary Lecture

Improving actions of natural foods and Ninjin’yoeito (a herbal medicine) on diabetes mellitus symptoms via improvement of interstitial fluid pH
International Conference on Natural Toxicology and Pharmacology.
2019.08.07-10, Guangzhou, China

国際学会 一般講演(ポスター含む)

326.
Puppulin L, Hosogi S, Tanaka H, MARUNAKA Y
Highly localized pH sensing on the outer membrane of cells using
surface enhanced Raman spectroscopy
The 9th Congress of Federation of Asian and Oceanian Physiological Societies.
2019.03.28-31, Kobe, Japan
J Physiol Sci 69:S271, 2019

325.
Ikeuchi Y, Kogiso H, Tanaka S, Hosogi S, Nakahari T, Asano S, MARUNAKA Y
Airway ciliary beating activated by enhanced Ca2+ signal in Hochuekki-to (TJ-41) treated mice
The 9th Congress of Federation of Asian and Oceanian Physiological Societies. 2019.03.28-31, Kobe, Japan
J Physiol Sci 69:S268, 2019

324.
Kogiso H, Ikeuchi Y, Tanaka S, Hosogi S, Shimamoto C, Raveau M, Yamakawa K, Nakahari T, Asano S, MARUNAKA Y
Inhibition of the frequency of airway ciliary beating by PDE1
activation in Down syndrome mouse
The 9th Congress of Federation of Asian and Oceanian Physiological Societies. 2019.03.28-31, Kobe, Japan
J Physiol Sci 69:S266, 2019

323.
Marunaka R, MARUNAKA Y
Aldosterone action on epithelial Na+ channel trafficking under the
insulin-stimulated condition
The 9th Congress of Federation of Asian and Oceanian Physiological Societies. 2019.03.28-31, Kobe, Japan
J Physiol Sci 69:S252, 2019

322.
Kuwahara Y, Kato I, Kuwahara A, MARUNAKA Y
Neurogenic relaxation of Xenin on spontaneous circular muscle
contractions in rat distal colon
The 9th Congress of Federation of Asian and Oceanian Physiological Societies. 2019.03.28-31, Kobe, Japan
J Physiol Sci 69:S164, 2019

321.
Harata D, Asano J, Kuwahara A, Inui T, MARUNAKA Y
Secretory reflex pathway of SCFA in the rat distal colon
The 9th Congress of Federation of Asian and Oceanian Physiological Societies. 2019.03.28-31, Kobe, Japan
J Physiol Sci 69:S163, 2019

320.
Kuwahara A, Kuwahara Y, Kato I, Inui T, MARUNAKA Y
Secretory reflex pathway of Xenin-25 in the rat ileum
The 9th Congress of Federation of Asian and Oceanian Physiological Societies. 2019.03.28-31, Kobe, Japan
J Physiol Sci 69:S163, 2019

319.
Sun H, MARUNAKA Y, Asano S
Involvement of EP receptors in the regulation of Short circuit
current by prostaglandins in A6 cells
The 9th Congress of Federation of Asian and Oceanian Physiological Societies. 2019.03.28-31, Kobe, Japan
J Physiol Sci 69:S162, 2019

国内学会シンポジウム、ワークショップ、パネルディスカッションなど

1) MARUNAKA Y
Invited Lecture
Improving action of Ninji’yoeito on the syndrome of diabetes mellitus.
The 62th Annual Meeting of the Japan Diabetes Society.
2019.05.24, Sendai, Japan

国内学会  一般講演(ポスター含む)

近畿生理学談話会

科研費

1) 丸中良典(研究代表者) 基盤研究(B) (一般) (継続、2018年〜2021年)「食品成分による間質液pH制御を介した糖尿病・アルツハイマー型認知症発症予防法開発」

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