医学における生命現象・疾病発症の総合的・統合的メカニズム解明を目指し研究を進めています。

Publication list of Prof. Yoshinori MARUNAKA

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200.
Taruno A, Sun H, Nakajo K, Murakami T, Ohsaki Y, Kido MA, Ono F, MARUNAKA Y
Post-translational palmitoylation controls the voltage gating and lipid raft association of CALHM1 channel
J Physiol (London) 595(18):6121-6145, 2017

199.
Puppulin P, Pezzotti G, Sun H, Hosogi S, Nakahari T, Inui T, Kumamoto Y, Tanaka H, MARUNAKA Y
Raman micro-spectroscopy as a viable tool to monitor and estimate the ionic transport in epithelial cells
Scientific Reports 7(1):3395, 2017

198.
Kogiso H, Hosogi S, Ikeuchi Y, Tanaka S, Shimamoto C, Matsumura H, Nakano T, Sano K, Inui T, MARUNAKA Y, Nakahari T
A low [Ca2+]i-induced enhancement of cAMP-activated ciliary beating by PDE1A inhibition in mouse airway cilia
Pflügers Archiv – Eur J Physiol 469(9):1215-1227, 2017

197.
Tanaka S, Miyazaki H, Shiozaki A, Ichikawa D, Otsuji E, MARUNAKA Y
Cytosolic Cl affects the anticancer activity of paclitaxel in the gastric cancer cell line, MKN28 cell
Cell Physiol Biochem 42:68-80, 2017

196.
MARUNAKA Y
Actions of quercetin, a flavonoid, on ion transporters: its physiological roles
Annals of the New York Academy of Sciences 1398(1):142-151, 2017

195.
Sasamoto K, Marunaka R, Niisato N, Sun H, Taruno A, Pezzottia G, Yamamoto T, Kanamura N, Zhu W, Nishio K, Inui T, Eaton DC, MARUNAKA Y
Analysis of aprotinin, a protease inhibitor, action on the trafficking of epithelial Na+ channels (ENaC) in renal epithelial cells using a mathematical model
Cell Physiol Biochem 41:1865-1880, 2017

194.
Kudou M, Shiozaki A, Kosuga T, Shimizu H, Ichikawa D, Konishi H, Morimura R, Komatsu S, Ikoma H, Fujiwara H, Okamoto K, MARUNAKA Y, Otsuji E.
Heat shock exerts anticancer effects on liver cancer via autophagic degradation of aquaporin
Int J Oncol 50(5):1857-1867, 2017.

193.
Shiozaki A, Ichikawa D, Kosuga T, MARUNAKA Y, Otsuji E.
Regulation of osmolality for cancer treatment.
J Physiol Sci 67(3):353-360, 2017.

192.
MARUNAKA Y, Marunaka R, Sun H, Yamamoto T, Kanamura N, Inui T, Taruno A.
Actions of quercetin, a polyphenol, on blood pressure.
Molecules 22(2). pii: E209, 2017.

191.
Taruno A, MARUNAKA Y.
Hypotonicity activates a voltage-dependent membrane conductance in N2a neuroblastoma cells.
Biochem Biophys Res Commun 484(2):331-335, 2017.

190.
Ariyoshi Y, Shiozaki A, Ichikawa D, Shimizu H, Kosuga T, Konishi H, Komatsu S, Fujiwara H, Okamoto K, Kishimoto M, MARUNAKA Y, Otsuji E.
Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.
Oncotarget 8(2):2209-2223, 2017

189.
Yoshimoto K, Nagao M, Watanabe Y, Yamaguchi T, Ueda S, Kitamura Y, Nishimura K, Inden M, MARUNAKA Y, Hattori H, Murakami K, Tokaji M, Ochi K.
Enhanced alcohol-drinking behavior associated with active ghrelinergic and serotoninergic neurons in the lateral hypothalamus and amygdala.
Pharmacol Biochem Behavior 153:1-11, 2017

188.
Shiozaki A, Kudou M, Ichikawa D, Shimizu H, Arita T, Kosuga T, Konishi H, Komatsu S, Fujiwara H, Okamoto K, Kishimoto M, MARUNAKA Y, Otsuji E.
Expression and role of anion exchanger 1 in esophageal squamous cell carcinoma
Oncotarget 8(11):17921-17935, 2017

187.
Taruno A, Kashio M, Sun H, Kobayashi K, Sano H, Nambu A, MARUNAKA Y
Adeno-associated virus-mediated gene transfer into taste cells in vivo
Chemical Senses 42(1):69-78, 2017

186.
Pezzotti G, Adachi T, Gasparutti I, Vincini G, Zhu W, Boffelli M, Rondinella A, Marin E, Ichioka H, Yamamoto T, MARUNAKA Y, Kanamura N
Vibrational monitor of early demineralization in tooth enamel after in vitro exposure to phosphoridic liquid
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 173:19-33, 2017

185.
Nakajima K, MARUNAKA Y
Intracellular chloride ion concentration in differentiating neuronal cell and its role in growing neurite
Biochem Biophys Res Commun 479(2):338-342, 2016

184.
Pezzotti G, McEntire BJ, BockR, Zhu W, Boschetto F, Rondinella A, Marin E, MARUNAKA Y, Adachi T, Yamamoto T, Kanamura N, Bal BS
In situ spectroscopic screening of osteosarcoma living cells on stoichiometry-modulated silicon nitride bioceramic surfaces
ACS Biomater Sci Eng 2 (7): 1121-1134, 2016

183.
MARUNAKA Y, Marunaka R, Sun H, Yamamoto T, Kanamura N, Taruno A
Na+ homeostasis by epithelial Na+ channel (ENaC) and Nax channel (Nax): cooperation of ENaC and Nax
Annals of Translational Medicine 4(Suppl 1):S11, 2016.

182.
Kudou M, Shiozaki A, Kosuga T, IchikawaD, Konishi H, Morimura R, Komatsu S, Ikoma H, Fujiwara H, Okamoto K, Hosogi S, Nakahari T, MARUNAKA Y, Otsuji E
Inhibition of regulatory volume decrease enhances the cytocidal effect of hypotonic shock in hepatocellular carcinoma
J Cancer 7(11):1524-1533, 2016

181.
Puppulin L, Miura Y, Casagrande E, Hasegawa M, MARUNAKA Y, Tone S, Sudo A, Pezzotti G
Validation of a protocol based on Raman and Infrared spectroscopies to nondestructively estimate the oxidative degradation of UHMWPE used in total joint arthroplasty
Acta Biomaterialia 38:168-178, 2016

180.
Tanaka S, Hosogi S, Sawabe Y, Shimamoto C, Matsumura H, Inui T, MARUNAKA Y, Nakahari T
PPARα activation of NOS1 via PI3K/Akt in guinea pig antral mucous cells: NO-enhancement in enhancement of Ca2+-regulated exocytosis
Biomed Res 37:167-178, 2016

179.
Kimura T, Hashimoto Y, Tanaka M, Asano M, Yamazaki M, Oda Y, Toda H, MARUNAKA Y, Nakamura N, Fukui M
Sodium-chloride difference and metabolic syndrome: a population-based large-scale cohort Study
Internal Medicine 55(21):3085-3090, 2016

178.
Pezzotti G, Bock RM, McEntire BJ, Jones E, Boffelli M, Zhu W, Baggio G, Boschetto F, Puppulin L, Adachi T, Yamamoto T, Kanamura N, MARUNAKA Y, Bal BS
Silicon nitride bioceramics induce chemically driven lysis in porphyromonas gingivalis.
Langmuir 32:3024-3035, 2016

177.
Tsuji T, Matsuo K, Nakahari T, MARUNAKA Y, Yokoyama T
Structural basis of the Inv compartment and ciliary abnormalities in inv/nphp2 mutant mice
Cytoskeleton 73:45-56, 2016

176.
Sasamoto K, Niisato N, Taruno A, MARUNAKA Y
Simulation of Cl secretion in epithelial tissues: New methodology estimating activity of electro-neutral Cl transporter
Frontiers in Physiology 6:370, 2015

175.
Pezzotti G, Puppulin L, La Rosa A, Boffelli M, Zhu W, McEntire BJ, Hosogi S, Nakahari T, MARUNAKA Y
Effect of pH and monovalent cations on the Raman spectrum of water: Basics revisited and application to measure concentration gradients at water/solid interface in Si3N4 biomaterial
Chemical Physics 463:120-136, 2015

174.
Ochi F, Shiozaki A, Ichikawa D, Fujiwara H, Nakashima S, Takemoto K, Kosuga T, Konishi H, Komatsu S, Okamoto K, Kishimoto M, MARUNAKA Y, Otsuji E
Carbonic anhydrase XII as an independent prognostic factor in advanced esophageal squamous cell carcinoma
J Cancer 6:922-929, 2015

173.
Pezzotti G, Boffelli M, Miyamori D, Uemura T, MARUNAKA Y, Zhu W, Ikegaya H
Raman spectroscopy of human skin: looking for a quantitative algorithm to reliably estimate human age
J Biomed Optics 20:65008, 2015

172.
Fukuda T, Fukui M, Tanaka M, Senmaru T, Iwase H, Yamazaki M, Aoi W, Inui T, Nakamura N, MARUNAKA Y
Effect of Brazilian green propolis in patients with type 2 diabetes: A double blind randomized placebo-controlled study
Biomedical Reports 3: 355-360, 2015

171.
Pezzotti G, Zhu W, Boffelli M, AdachiT, Ichioka H, Yamamoto T, MARUNAKA Y, Kanamura N
Vibrational algorithms for quantitative crystallographic analyses of hydroxyapatite-based biomaterials: I, Theoretical foundations
Anal Bioanal Chem 407:3325-42, 2015

170.
Tomoda A, MARUNAKA Y, Eaton DC, Dinudom A
Membrane Transport: Ionic Environments, Signal Transduction, and Development of Therapeutic Targets
BioMed Res Int 2015:581626, 2015

169.
MARUNAKA Y
Roles of interstitial fluid pH in diabetes mellitus: Glycolysis and mitochondrial function
World J Diabetes 6:125-135, 2015

168.
Hatano R, Akiyama K, Tamura A, Hosogi S, MARUNAKA Y, Caplan MJ, Ueno Y, Tsukita S, Asano S.
Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium.
Hepatology 61:1660-1671, 2015

167.
Takemoto K, Shiozaki A, IchikawaD, Komatsu S, Konishi H, Nako Y, Murayama Y, Kuriu Y, Nakanishi M, Fujiwara H, Okamoto K, Sakakura C, Nakahari T, MARUNAKA Y, Otuji E
Evaluation of the efficacy of peritoneal lavage with distilled water in colorectal cancer surgery – in vitro and in vivo study
J Gastroenterol 50:287-97, 2015

166.
Shiozaki A, Ichikawa D, Fujiwara H, Otsuji E, MARUNAKA Y
Progress in Cellular Physiological Researches on Esophageal Cancer
J Tumor 2:252-256, 2014

165.
Tanaka S, Sugiyama N, Takahashi Y, Mantoku D, Sawabe Y, Kuwabara H, Nakano T, Shimamoto C, Matsumura H, MARUNAKA Y, Nakahari T
PPARα autocrine regulation of Ca2+-regulated exocytosis in guinea pig antral mucous cells: NO and cGMP accumulation.
Am J Physiol Gastrointest Liver Physiol 307:G1169-1179, 2014

164.
Sun H, Niisato N, Inui T, MARUNAKA Y
Insulin is involved in transcriptional regulation of NKCC and CFTR Cl channel through PI3K activation and ERK inactivation in renal epithelial cells
J Physiol Sci 64:433-43, 2014

163.
Aoi W, MARUNAKA Y
Importance of pH homeostasis in metabolic health and diseases: crucial role of membrane proton transport
BioMed Res Int 2014:598986, 2014

162.
Yuan Y, Wang X, Lu X, MARUNAKA Y, Wang X
Effect of Coptidis Rhizoma extracts in a water-based solution on insulin resistance in 3T3-L1 adipocytes
Biomed Res 35:321-327, 2014

161.
MARUNAKA Y
Characteristics and pharmacological regulation of epithelial Na+ channel (ENaC) and epithelial Na+ transport
J Pharmacol Sci 126:21-36, 2014

160.
Shiozaki A, Takemoto K, Ichikawa D, Kosuga T, Konishi H, Komatsu S, Fujiwara H, Okamoto K, Kishimoto M, MARUNAKA Y, Otsuji E
The K-Cl cotransporter KCC3 as an independent prognostic factor in human esophageal squamous cell carcinoma
BioMed Res Int 2014:936401, 2014

159.
Shiozaki A, Ichikawa D, Takemoto K, Nako Y, Nakashima S, Shimizu H, Kitagawa M, Kosuga T, Konishi H, Komatsu S, Fujiwara H, Okamoto K, MARUNAKA Y, Otsuji E
Efficacy of a hypotonic treatment for peritoneal dissemination from gastric cancer cells-An in vivo evaluation
BioMed Res Int 2014:707089, 2014

158.
Shiozaki A, Nako Y, Ichikawa D, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, MARUNAKA Y, Otsuji E
Role of the Na+/K+/2Cl cotransporter NKCC1 in cell cycle progression in human esophageal squamous cell carcinoma
World J Gastroenterol 20:6844-6859, 2014

157.
Sun H, Niisato N, Nishio K, Hamilton KL, MARUNAKA Y
Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl secretion : useful tools as regulators of Cl secretion
BioMed Res Int 2014:902735, 2104

156.
MARUNAKA Y
Importance of expression and function of angiotensin II receptor type 1 in pulmonary epithelial cells
Respiratory Physiol Neurobiol 196:39-42, 2014

155.
Hayata H, Miyazaki H, Niisato N, Yokoyama N, MARUNAKA Y
Lowered extracellular pH is involved in the pathogenesis of skeletal muscle insulin resistance
Biochem Biophys Res Commun 445:170-174, 2014

154.
Hosogi S, Kusuzaki K, Inui T, Wang X, MARUNAKA Y
Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell
J Cell Mol Med 18:1124-1133, 2014

153.
Shiozaki A, Ishikawa D, Otsuji E, MARUNAKA Y
Cellular Physiological Approach for Treatment of Gastric Cancer
World J Gastroenterol 20:11560-11566, 2014

152.
MARUNAKA Y
Roles of ionic environments in growth of human cancer cell and potentials of ion transporter blockers in cancer therapies
J Gastrointestinal and Digestive System 3:163, 2014

151.
Aoi W, MARUNAKA Y
The Importance of regulation of body fluid pH in the development and progression of Metabolic Diseases
Advances in Medicine and Biology Vol.77, pp. 177-189, 2014
Nova Publishers

150.
MARUNAKA Y, Yoshimoto K, Aoi W, Hosogi S, Ikegaya H
Low pH of interstitial fluid around hippocampus of the brain in diabetic OLETF rats
Molecular and Cellular Therapies 2:6, 2014

149.
Kitagawa M, Niisato N, Shiozaki A, Ohta-Fujimoto M, Hosogi S, Miyazaki H, Ichikawa D, Otsuji E, MARUNAKA Y
A regulatory role of K+-Cl cotransporter in the cell cycle progression of breast cancer MDA-MB-231 cells.
Arch Biochem Biophys 539:92-98, 2013

148.
Tanaka S, Tanaka R, Harada S, Kohda Y, Matsumura H, Shimamoto C, Sawabe Y, MARUNAKA Y, Kuwabara H, Takahashi Y, Ito S, Nakahari T.
A PKG inhibitor increases Ca2+-regulated exocytosis in guinea pig antral mucous cells: cAMP accumulation via PDE2A inhibition
Am J Physiol Gastrointest Liver Physiol 304:G773-G780, 2013

147.
Aoi W, Hosogi S, Niisato N, Yokoyama N, Hayata H, Miyazaki H, Kusuzaki K, Fukuda T, Fukui M, Nakamura N, MARUNAKA Y
Improvement of insulin resistance, blood pressure and interstitial pH in early developmental stage of insulin resistance in OLETF rats by intake of propolis
extracts.
Biochem Biophys Res Commun 432:650-653, 2013

146.
Hosogi S, Miyazaki H, Nakajima K, Ashihara E, Niisato N, Kusuzaki K, MARUNAKA Y.
An inhibitor of Na+/H+ exchanger (NHE), ethyl-Isopropyl Amiloride (EIPA), diminishes proliferation of MKN28 human gastric cancer cells by decreasing the cytosolic Cl concentration via DIDS-Sensitive pathways.
Cell Physiol Biochem. 30:1241-1253, 2012.

145.
Nako Y, Shiozaki A, Ichikawa D, Komatsu S, Konishi H, Iitaka D, Ishii H, Ikoma H, Kubota T, Fujiwara H, Okamoto K, Ochiai T, Nakahari T, MARUNAKA Y, Otsu E
Enhancement of the cytocidal effects of hypotonic solution using a chloride channel blocker in pancreatic cancer cells
Pancreatology 12:440-448, 2012.

144.
Nakajima K, Niisato N, MARUNAKA Y
Enhancement of tubulin polymerization by Cl-induced blockade of intrinsic GTPase
Biochem Biophys Res Commun 425:225-229, 2012

143.
Nagao H, Nakajima K, Niisato N, Hirota R, Bando H, Sakaguchi H, Hisa Y, MARUNAKA Y
K+-Cl cotransporter 1 (KCC1) negatively regulates NGF-induced neurite outgrowth in PC12 cells
Cell Physiol Biochem 30:538-551, 2012

142.
Niisato N, Ohta M, Eaton DC, MARUNAKA Y.
Hypotonic stress upregulates beta- and gamma-ENaC expression through suppression of ERK by inducing MKP-1.
Am J Physiol (Renal Physiol) 303:F240-252, 2012

141.
Kusuzaki K, Hosogi S, Ashihara E, Matsubara T, Satonaka H, Nakamura T, Matsumine A, Sudo A, Uchida A, Murata H, Baldini N, Fais S, MARUNAKA Y.
Translational Research of Photodynamic Therapy with Acridine Orange which Targets Cancer Acidity.
Current Pharmaceutical Design 18:1414-1420, 2012.

140.
Kusuzaki K, Hosogi S, Ashihara E, Matsubara T, Satonaka H, Nakamura T, Matsumine A, Sudo A, Uchida A, Murata H, Baldini N, Fais S, MARUNAKA Y
New Concept of Limb Salvage Surgery in Musculoskeletal Sarcomas with Acridine Orange Therapy
In: Sarcoma: Symptoms, Causes and Treatments (Editor: Butler EJ)
pp. 124-137, Nova Science Publishers, New York, 2012

139.
Niisato N, MARUNAKA Y
Sensing mechanism of stretch activated ion channels
Mechanically Gated Channels and mechanisms of their regulation 6:189-213, 2012
Springer

138.
Komatani-Tamiya N, Daikoku E, Takemura Y, Shimamoto C, Nakano T, Iwasaki Y, Matsumura H, MARUNAKA Y, Nakahari T.
Procaterol-stimulated increases in ciliary bend amplitude and ciliary beat frequency in mouse bronchioles
Cell Physiol Biochem 29:511-522, 2012

137.
Iitaka D, Shiozaki A, Ichikawa D, Kosuga T, Komatsu S, Okamaoto K, Fujiwara H, Ishii H, Nakahari T, MARUNAKA Y, Otsuji E.
Blockade of chloride ion transport enhances the cytocidal effect of hypotonic solution in gastric cancer cells.
J Surgical Res 176:524-534, 2012

136.
Nakajima K, Niisato N, MARUNAKA Y
Genistein enhances the NGF-induced neurite outgrowth.
Biomed Res 32:351-356, 2011

135.
Shiozaki A, Otsuji E, MARUNAKA Y
Intracellular chloride regulates the G1/S cell cycle progression in gastric cancer cells
World J Gastrointest Oncol 3:119-122, 2011

134.
MARUNAKA Y, Niisato N, Taruno A, Ohta M, Miyazaki M, Hosogi S, Nakajima K, Kusuzaki K, Ashihara E, Nishio K, Iwasaki Y, Nakahari T, Kubota T.
Regulation of epithelial sodium transport via epithelial Na+ channel (ENaC)
J Biomed Biotechnol 2011:978196, 2011

133.
Nakajima K, Niisato N, MARUNAKA Y
Quercetin stimulates NGF-induced neurite outgrowth in PC12 cells via activation of Na+/K+/2Cl cotransporter
Cell Physiol Biochem 28:147-156, 2011

132.
Kosuga T, Shiozaki A, Ichikawa D, Fujiwara H, Komatsu S, Iitaka D, Tsujiura M, Morimura R, Takeshita H, Nagata H, Okamoto K, Nakahari T, MARUNAKA Y, Otsuji E
Pleural lavage with distilled water during surgery for esophageal squamous cell carcinoma
Oncology Reports 26:577-586, 2011

131.
Hashimoto-Gotoh T, Iwabe N, Tsujimura A, Nakagawa M, MARUNAKA Y
KF-1 Ubiquitin Ligase: Anxiety Suppressor Model
Cell Biochem Biophys 60:69–75, 2011

130.
Taruno A, MARUNAKA Y
Analysis of blocker-labeled channels reveals the dependence of recycling rates of ENaC on the total amount of recycled channels
Cell Physiol Biochem 26:925-934, 2010

129.
Matsubara T, Kusuzaki K, Matsumine A, Murata H, MARUNAKA Y, Hosogi S, Uchida A, Sudo A.
Photodynamic therapy with acridine orange in musculoskeletal sarcomas.
J Bone Joint Surg Br 92:760-762, 2010

128.
Sawabe Y, Shimamoto C, Sakai A, Kuwabara H, Saad AH, Nakano T, Takitani K, Tamai H, Mori H, MARUNAKA Y, Nakahari T.
PPAR-alpha modulation of Ca2+-regulated exocytosis via arachidonic acid in guinea pig antral mucous cells.
Exp Physiol 95:858-868, 2010

127.
Tokuda S, Miyazaki H, Nakajima K, Yamada T, MARUNAKA Y.
NaCl flux between apical and basolateral side recruits claudin-1 to tight junction strands and regulate paracellular transport.
Biochem Biophys Res Commun 393:390-396, 2010

126.
Ohsawa R, Miyazaki, Niisato N, Shiozaki A, Iwasaki Y, Otsuji E, MARUNAKA Y.
Intracellular chloride regulates cell proliferation through the activation of stress-activated protein kinases in MKN28 human gastric cancer cells.
J Cell Physiol 223:764-770, 2010

125.
Hiraoka K, Miyazaki H, Niisato N, Iwasaki Y, Kawauchi A, Miki T, MARUNAKA Y.
Chloride ion modulates cell proliferation of human androgen-independent prostatic cancer cell.
Cell Physiol Biochem 25:379-388, 2010

124.
Tokuda S, Miyazaki H, Nakajima K, Yamada T, MARUNAKA Y.
Hydrostatic pressure regulates tight junctions, actin cytoskeleton and transcellular ion transport.
Biochem Biophys Res Commun 390:1315-1321, 2009

123.
Hiramatsu A, Iwasaki Y, Koyama Y, Tamiya N, Hosogi S, Nakanishi M, Kohno Y, Ueda M, Arimoto T, MARUNAKA Y.
Phase II Trial of Weekly Gemcitabine and Split-dose Cisplatin for Advanced Non-small-cell Lung Cancer.
Jpn J Clin Oncol 39:779-783, 2009

122.
Tokuda S, Niisato N, Nagai T, Taruno A, Nakajima K, Miyazaki H, Yamada T, Hosogi S, Ohta M, Nishio K, Iwasaki MARUNAKA Y.
Regulation of paracellular Na+ and Cl conductances by hydrostatic pressure
Cell Biol Int 33:949-956, 2009.

121.
Yamada T, Niisato N, MARUNAKA Y.
Effects of extracellular chloride ion on epithelial sodium channel (ENaC) in arginine vasotocin (AVT)-stimulated renal epithelial cells.
Biomed Res 30:193-198, 2009

120.
Asano J, Niisato N, Nakajima K, Miyazaki H, Yasuda M, Iwasaki Y, Hama T, Dejima K, Hisa Y, MARUNAKA Y.
Quercetin stimulates NKCC1 via a PTK-dependent mechanism in human airway epithelium
Am J Resp Cell Mol Biol 41:688-695, 2009

119.
Yamada T, Takemura Y, Niisato N, Mitsuyama E, Iwasaki MARUNAKA Y.
Action of N-acylated ambroxol derivatives on secretion of chloride ions in human airway epithelia.
Biochem Biophys Res Commun 380:586-590, 2009.

118.
Maki M, Miyazaki H, Niisato N, Morihara M, MARUNAKA Y, Kubo T.
Blockers of K+/Cl transporter/channels diminish proliferation of osteoblastic cells.
Biomed Res 30:137-140, 2009.

117.
Sugino H, Futamura T, Mitsumoto Y, Maeda K, MARUNAKA Y
Atypical antipsychotics suppress production of proinflammatory cytokines and up-regulate interleukin-10 in lipopolysaccharide-treated mice.
Prog Neuropsychopharmacol Biol Psychiatry 33:303-307, 2009.

116.
Muroyama A, Inaka M, Matsushima H, Sugino H, MARUNAKA Y, Mitsumoto Y. Enhanced susceptibility to MPTP neurotoxicity in magnesium-deficient C57BL/6N mice.
Neurosci Res 63:72-75, 2009.

115.
Hosogi S, Iwasaki, Yamada T, Komatani-Tamiya, Hiramatsu A, Kohno Y, Ueda M, Arimoto T, MARUNAKA Y.
Effect of inducible nitric oxide synthase on apoptosis in Candia-induced acute lung injury
Biomed Res 29:257-266, 2008.

114.
Tokuda S, Niisato N, Nakajima K, MARUNAKA Y.
Regulation of the paracellular Na+ and Cl conductances by the NaClgenerated osmotic gradient in a manner dependent on the direction of osmotic gradients.
Biochem Biophys Res Commun 366:464-470, 2008.

113.
Miyazaki H, Shiozaki A, Niisato N, Ohsawa R, Itoi H, Ueda Y, Otsuji E, Yamagishi H, Iwasaki Y, Nakano T, Nakahari T, MARUNAKA Y.
Chloride ions control the G1/S cell-cycle checkpoint by regulating the expression of p21 through a p53-independent pathway in human gastric cancer cells.
Biochem Biophys Res Commun 366:506-512, 2008.

112.
Taruno A, Niisato N, MARUNAKA Y.
Intracellular calcium plays a role as the second messenger of hypotonic stress in gene regulation of SGK1 and ENaC in renal epithelial A6 cells.
Am J Physiol Renal Physiol 294:F177-286, 2008.

111.
Niisato N, MARUNAKA Y.
Osmortransduction through volume-sensitive Cl channels.
Mechanosensitive ion channels / Mechanosensitivity in Cells and Tissues. Vol. 1, 179-202, 2008 (Springer)

110.
Tokuda S, Niisato N, MARUNAKA Y.
Regulation of paracellular ion conductances by NaCl gradients in renal epithelial cells
Biochem Biophys Res Commun 363:566-471, 2007.

109.
Yasuda M, Niisato N, Miyazaki H, Iwasaki Y, Hama T, Dejima K, Hisa MARUNAKA Y.
Epithelial Na+ channel and ion transport in human nasal polyp and paranasal sinus mucosa
Biochem Biophys Res Commun 362:753-758, 2007.

108.
Maki M, Miyazaki H, Nakajima K, Yamane J, Niisato N, Morihara T, Kubo T, MARUNAKA Y.
Chloride-dependent acceleration of cell cycle via modulation of Rb and cdc2 in osteoblastic cells
Biochem Biophys Res Commun 361:1038-1043, 2007.

107.
Niisato N, Taruno A, MARUNAKA Y.
Aldosterone-induced modification of osmoregulated ENaC trafficking
Biochem Biophys Res Commun 361:162-168, 2007.

106.
Nakajima K, Miyazaki H, Niisato N, MARUNAKA Y.
Essential role of NKCC1 in NGF-induced neurite outgrowth.
Biochem Biophys Res Commun 359:604-610, 2007.

105.
Niisato N, Taruno A, MARUNAKA Y.
Involvement of p38 MAPK in hypotonic stress-induced stimulation of beta- and gamma-ENaC expression in renal epithelium.
Biochem Biophys Res Commun 358:819-824, 2007.

104.
Tokuda S, Shimamoto C, Yoshida H, Murao H, Kishima G, Ito S, Kubota T, Hanafusa T, Sugimoto T, Niisato N, MARUNAKA Y, Nakahari T.
HCO3 dependent pHi recovery and overacidification induced by NH4+ pulse in rat lung alveolar type II cells: HCO3 dependent NH3 excretion from lungs?
Pfluegers Arch (Eur J Physiol) 455:223-239, 2007.

103.
Aoi W, Niisato N, Sawabe Y, Miyazaki H, Tokuda S, Nishio K, Yoshikawa T, MARUNAKA Y.
Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt–sensitively hypertensive rats
Cell Biol Int 31:1288-1291, 2007.

102.
Ohsugi S, Iwasaki Y, Takemura Y, Nagata K, Harada H, Yokomura I, Hosogi S, Yuba T, Niisato N, Miyazaki H, Matsubara H, Fushiki S, MARUNAKA Y.
An inhaled inducible nitric oxide synthase inhibitor reduces damage of Candida-induced acute lung injury
Biomed Res 28:91-99, 2007.

101.
Taruno A, Niisato N, MARUNAKA Y.
Hypotonicity stimulates renal epithelial sodium transport by activating JNK via receptor tyrosine kinases.
Am J Physiol Renal Physiol 293:F128-138, 2007.

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