医学における生命現象・疾病発症の総合的・統合的メカニズム解明を目指し研究を進めています。

研究費

Japan Society of The Promotion of Science
Prevention of diabetes mellitus and Alzheimer dementia via improvement of low interstitial fluid pH by food constituent (2018-2021)
¥17,420,000

KIT-KPUM-KPU-KPhU Collaborative Research Grant
Roles of interstitial fluid pH in development for type 2 diabetes and the Alzheimer’s dementia and molecular mechanisms of regulation of interstitial fluid (2015 – 2016)

¥2,000,000

Kyoto-Funding for Innovation in Health-related R&D Fields
Development of apparatus measuring interstitial fluid pH as a biomarker for early diagnosis of type 2 diabetes and Alzheimer’s dementia (2015-2016)
¥1,300,000

Japan Society of The Promotion of Science
Development of non-invasive methods measuring interstitial fluid pH and HCO3- concentration by MRI and Raman (2015-2017)
¥3,770,000

Japan Society of The Promotion of Science
New targeting mechanisms of plasma proteins to proteasome (2015-2018)
¥4,9740,000

Yamada Research Grant
The prevention of Alzheimer’s disease through regulation of amyloid beta synthesis and brake-down by propolis intake (2013 – 2014)
¥4,900,000

Four-University Collaborative Research Grant
Molecular cell mechanisms of interstitial pH-mediated appearance of insulin resistance in diabetes mellitus (2013 – 2014)

¥2,000,000

Japan Society of The Promotion of Science
Continuous pH measurement of interstitial fluid and clarification of pathogenic mechanism of insulin resistance by ISFET pH sensor (2013-2015)
¥3,770,000

Japan Society of The Promotion of Science
Clarification of tumor metastatic mechanism caused by disturbance of WNK kinase-dependent Cl- transporter (2013-1016)
¥5,200,000

Four-University Collaborative Research Grant
Development of new system for drug delivery specific to cancer cells (2012 – 2013)
¥1,150,000

Japan Science and Technology Agency
Adaptable and Seamless Technology Transfer Program through Target-Driven R&D (A-STEP)
Feasibility Study Stage: Exploratory Research
Establishment of human interstitial fluid pH measurement technology: Prevention of diabetes mellitus and development of body fluid management method for management of pathophysiological condition (2012-2013)
¥1,700,000

Yamada Research Grant
The prevention of diabetes and its complications through the insulin-resistant improvement by propolis intake (2012 – 2013)
¥6,802,000

The Salt Science Research Foundation

Molecular Mechanisms of aldosterone-regulation of ENaC protein (2012-2013)
¥950,000

Japan Society of The Promotion of Science
Flavonoid regulation of salt-sensitive hypertension via ENaC (2012-2015)
¥5,330,000

Japan Society of The Promotion of Science
Prevention of neuron death via Cl–mediated regulation of small G protein (2012-2015)
¥5,460,000

Yamada Research Grant
Mechanisms of propolis-induced improvement of insulin resistance in diabetes mellitus type II patients and clinical application (2011 – 2012)
¥5,485,000

Japan Science and Technology Agency
Adaptable and Seamless Technology Transfer Program through Target-Driven R&D (A-STEP)
Feasibility Study Stage: Exploratory Research
Establishment of molecule-target anti-cancer technology using new cancer specific DDS based on lipid composition of exosome (2011-2012)
¥3,000,000

Japan Society of The Promotion of Science
HGF-dependent recovery mechanisms form LPS-induced lung injury (2011-2014)
¥5,330,000

Kyoto Innovation Collaboration Center
Promoting Business-Academia Collaboration Grant for Fusion of Arts and Humanities
Protection of children health by opening dream restaurant for food education
– Project of new menu developing food education for children – (2011)
¥900,000

The Salt Science Research Foundation
Development of new drugs targeting ion transporters expressed in cancer stem cells (2011-2012)
¥900,000

Japan Society of The Promotion of Science
Ion transporter targeting therapy for hormone-insensitive prostate cancer (2010-2012)
¥2,900,000

The Salt Science, Research Foundation
Molecular mechanisms of neurite elongation by flavonoids (2010-2011)
¥900,000

Fuji Protein Research Foundation
Activation of immune cell by genistein (2010-2011)
¥1,000,000

Japan Society of The Promotion of Science
Trafficking mechanisms of ENaC regulated by protease (2008-2012)
¥19,500,000

Japan Society of The Promotion of Science
Roles of TLR in endotoxin-induced lung injury (2008-2011)
¥3,700,000

Fuji Protein Research Foundation
Molecular Mechanisms of Neurite elongation by Flavonoids (2008-2009)
¥1,000,000

The Salt Science Research Foundation
Regulation of ENaC protein lifetime by protease (2008-2009)
¥1,500,000

Japan Society of The Promotion of Science
Molecular mechanisms of cell death regulated by chloride ion-mediated Akt/JNK (2007-2009)
¥3,500,000

The Salt Science Research Foundation
Osmosensing Mechanisms (2007-2008)
¥900,000

Japan Society of The Promotion of Science
Molecular Mechanisms of Chloride Ion Requirement for Cancer Cell Growth (2006-2007)
¥3,300,000

Japan Society of The Promotion of Science
Molecular Mechanisms of Aldosterone-induced abnormal regulation of ENaC-related body fluid imbalance (2005-2008)
¥14,100,000

Japan Society of The Promotion of Science
Molecular mechanisms of recovery from lung edema: roles of ENaC (2006-2008)
¥3,600,000

Japan Society of The Promotion of Science
Osmo-sensing mechanism and Regulation of ENaC Expression (2005-2007)
¥3,500,000

Fuji Protein Research Foundation
Regulatory Mechanisms of Salt-sensitive Hypertension by Flavonoids (2005-2006)
¥1,000,000

Japan Society of The Promotion of Science
Therapeutics for Brain Edema by Aldose Reductace Inhibitor (2003-2005)
¥3,300,000

Japan Society of The Promotion of Science
Molecular Mechanism of regulation of Na+ reabsorption by RVD/PAK (2003-2005)
¥3,300,000

The Salt Science Research Foundation
Regulation of Sodium transport in lung epithelium (2001-2003)
¥3,400,000

Japan Society of The Promotion of Science
Regulation of Chloride Transport by Tyrosine Kinase (2001-2003)
¥3,300,000

The Medical Research Council of Canada
Single Sodium Channel Regulation in Alveolar Epithelium (1999-2003)
$318,940

The Premier’s Research Excellence Award
Regulation of Sodium Transport in Fetal Lung Epithelium
The Government of Ontario (1999-2001)
$100,000

The Kidney Foundation of Canada
Regulation of Na+ transport by osmolality/protein tyrosine kinase in renal epithelium (1998-2000)
$80,000

The Ontario Thoracic Society (Canada)
Trafficking mechanisms of Amiloride-blockable Channels in Alveolar Cells (1996)
$9,186

The Kidney Foundation of Canada
Regulation of Na+ transport by ADH and osmolality in renal epithelium (1996 – 1998)
$80,000

The Medical Research Council of Canada
Characterization of rNEDD4:
A Candidate Regulatory Protein Interacting with the Epithelial Na Channel (1996 – 1998)
$108,138

The Ontario Thoracic Society (Canada)
Regulation of Amiloride-blockable Channels in Alveolar Cells (1995)
$8,123

The Kidney Foundation of Canada
Hormonal Regulation of Sodium Transport in Renal Epithelium (1994 – 1996)
$80,000

The Medical Research Council of Canada
Single Sodium Channel Regulation in Alveolar Epithelium (1993-1999)
$1,020,000

The Kidney Foundation of Canada
Regulation of Amiloride-blockable Na Channels in Renal Epithelium (1992 – 1994)
$80,000

The Ontario Thoracic Society (Canada)
Intracellular pH and Ca2+ Concentration in Alveolar Cells (1992)
$9,123

The Ontario Thoracic Society (Canada)
Current Fluctuation Analysis in Alveolar Cells (1992)
$7,800

Dean’s Fund, University of Toronto Faculty of Medicine
Signal Transduction of Insulin in Renal Epithelium (1992)
$10,000

The Ontario Thoracic Society (Canada)
Intracellular Ionic Concentration in Alveolar cells (1991)
$12,500

The Hospital for Sick Children Research Foundation (Canada)
Regulation of Ion Transport in Epithelial Tissues
(1991)
$11,500

The National Sanatorium Foundation (Canada)
Measurement of Cytosolic Ionic Concentration in Single Alveolar Cells” (1991)
$25,000

The Medical Research Council of Canada
Development and Regulation of Na channels in Lung Alveolar Cells” (1991 – 1993)
$218,600

The Heart and Stroke Foundation of Ontario
Na Channel Regulation in Reabsorption of Pulmonary Edema” (1991 – 1996)
$340,000

The National Kidney Foundation of Georgia (U.S.A.)
Regulation of Cl- Channels in a Distal Nephron Cell Line (1989 – 1990)
$20,500

The Ministry of Education, Science and Culture of Japan
The Regulation of Ion Transport in Pancreatic B Cells: Patch Clamp Techniques (1986 – 1987)
¥900,000

The Ministry of Education, Science and Culture of Japan
Electrical Properties of Pancreatic Beta Cells with Path Clamp Techniques (1985 – 1986)
¥900,000

The Ministry of Education, Science and Culture of Japan
Glucose-induced Depolarization in Pancreatic Beta Cells with Voltage Clamp Method (1984 – 1985)
¥900,000

The Ministry of Education, Science and Culture of Japan
Glucose-induced Depolarization in Pancreatic Beta Cells (1983 – 1984)
¥700,000

The Ministry of Education, Science and Culture of Japan
Ion and Glucose Transport in HeLa Cells: Optical Measurements (1982 – 1983)
¥800,000

お気軽にご連絡ください。 TEL 075-802-0131 内線 2322 受付時間 9:00 - 16:30 [ 土・日・祝日除く ]

PAGETOP
Copyright © 丸中良典研究室 All Rights Reserved.
Powered by WordPress & BizVektor Theme by Vektor,Inc. technology.