医学における生命現象・疾病発症の総合的・統合的メカニズム解明を目指し研究を進めています。

Publication list of Prof. Yoshinori MARUNAKA

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Publication list of Prof. Yoshinori MARUNAKA
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232.
Aoi W, Zou X, Xiao J, MARUNAKA Y
Body Fluid pH Balance in Metabolic Health and Possible Benefits of Dietary Alkaline Foods
eFood (in press)

231.
Mieno H, MARUNAKA Y, Inaba T, Kojima K, Yoneda K, Nagata K, Sotozono C
pH balance and lactic acid increase in the vitreous body of diabetes mellitus patients
Experimental Eye Research (in press)

230.
Inui TA, Yasuda M, Hirano S, Ikeuchi Y, Kogiso H, Inui T, MARUNAKA Y, Nakahari T
Enhancement of ciliary beat amplitude by carbocisteine in ciliated human nasal epithelial cells
Laryngoscope (in press)

229.
Konishi T, Shiozaki A, Kosuga T, Kudou M, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, MARUNAKA Y, Otsuji E
LRRC8A expression influences growth of esophageal squamous cell carcinoma
Am J Pathol (in press)

228.
Shiozaki A, Yamazato Y, Kosuga T, Kudou M, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, MARUNAKA Y, Otsuji E
Effect of low temperature on the regulation of cell volume after hypotonic shock in gastric cancer cells
Int J Oncol (in press)

227.
Inui TA, Murakami K, Yasuda M, Hirano S, Ikeuchi Y, Kogiso H, Hosogi S, Inui T, MARUNAKA Y, Nakahari T
Ciliary beating amplitude controlled by intracellular Cl and a high rate of CO2 production in ciliated human nasal epithelial cells
Pflügers Archiv – European Journal of Physiology 471(8):1127-1142, 2019

226.
Kuwahara A, Kuwahara Y, Kato I, Kawaguchi K, Harata D, Asano S, Inui T, and Marunaka Y
Xenin-25 induces anion secretion by activating non-cholinergic secretomotor neurons in the rat ileum
Am J Physiol Gastrointest Liver Physiol 316(6):G785-G796, 2019

225.
Pillai SR, Damaghi M, Marunaka Y, Spugnini EP, Fais S, Gillies RJ
Causes, consequences, and therapy of tumors acidosis
Cancer Metastasis Reviews 38(1-2):205-222, 2019

224.
Gillies RJ, Pilot C, MARUNAKA Y, Fais S
Targeting acidity in cancer and diabetes
Biochimica et Biophysica Acta Reviews on Cancer 1871(2):273-280, 2019

223.
Okada Y, Okada T, Sato-Numata K, Islam MR, Ando-Akatsuka Y, Numata T, Kubo M, Shimizu T, Kurbannazarova RS, MARUNAKA Y, Sabirov RZ
Cell Volume-Activated and -Related Anion Channels in Mammalian Cells: Their Biophysical, Molecular and Pharmacological Properties
Pharmacological Reviews 71(1):49-88, 2019

222.
Ikeuchi Y, Kogiso H, Hosogi S, Tanaka S, Shimamoto C, Matsumura H, Inui T, MARUNAKA Y, Nakahari T
Carbocisteine stimulated an increase in ciliary bend angle via a decrease in [Cl]i in mouse airway cilia
Pflügers Archiv – European Journal of Physiology 471:365-380, 2019

221.
Shiozaki A, Ariyoshi Y, Iitaka D, Kosuga T, Shimizu H, Kudou M, Konishi T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, MARUNAKA Y, Ichikawa D, Otsuji E.
Functional analysis and clinical significance of sodium iodide symporter expression in gastric cancer.
Gastric Cancer 22(3):473-485, 2019

220.
Inui T, Yasuda M, Hirano S, Ikeuchi Y, Kogiso H, Inui T, MARUNAKA Y, Nakahari T. Daidzein-stimulated increase in the ciliary beating amplitude via an [Cl]i decrease in ciliated human nasal epithelial cells
Int J Mol Sci 19:3754, 2018

219.
Puppulin P, Hosogi S, Sun H, Matsuo K, Inui T, Kumamoto Y, Suzaki T, Tanaka H, MARUNAKA Y
Bioconjugation strategy for cell surface labelling with gold nanostructures designed for highly localized pH measurement
Nature Communications 9(1) 5278, 2018

218.
Hosogi S, Ohsawa M, Kato I, Kuwahara A, Inui T, Inui A, MARUNAKA Y
Improvement of diabetes mellitus symptoms by intake of Ninjin’yoeito
Frontiers in Nutrition 5:112, 2018

217.
KuremotoT, Kogiso H, Yasuda M, Inui T, Murakami K, Hirano S, Ikeuchi Y, Hosogi S, Inui T, MARUNAKA Y, Nakahari T.
Spontaneous oscillation of the ciliary beat frequency regulated by release of Ca2+ from intracellular stores in mouse nasal epithelia
Biochem Biophys Res Commun 507:211-216, 2018

216.
MARUNAKA Y
The proposal of molecular mechanisms of weak organic acids intake-induced improvement of insulin resistance in diabetes mellitus via elevation of interstitial fluid pH
Int J Mol Sci 19(10):3244, 2018

215.
Marunaka R, Taruno A, Yamamoto T, Kanamura N, MARUNAKA Y
Action of protein tyrosine kinase inhibitors on the hypotonicity-stimulated trafficking kinetics of epithelial Na+ channels (ENaC) in renal epithelial cells: Analysis using a mathematical model.
Cell Physiol Biochm 50:363-377, 2018

214.
Yamazato Y, Shiozaki A, Ichikawa D, KosugaT, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, MARUNAKA Y, Otsuji E
Aquaporin 1 suppresses apoptosis and affects prognosis in esophageal squamous cell carcinoma
Oncotarget 9(52):29957-29974, 2018

213.
Shiozaki A, Hikami S, Ichikawa D, Kosuga T, Shimizu H, Kudou M, Yamazato Y, Kobayashi T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, MARUNAKA Y, Otsuji E
Anion exchanger 2 suppresses cellular movement and has prognostic significance in esophageal squamous cell carcinoma
Oncotarget 9(40):25993-26006, 2018

212.
Kobayashi T, Shiozaki A, Nako Y, Ichikawa D, Kosuga T, Shoda K, Arita T, Konishi H, Komatsu S, Kubota T, Fujiwara H, Okamoto K, Kishimoto M, Konishi E, MARUNAKA Y, Otsuji E.
Chloride intracellular channel 1 as a switch among tumor behaviors in human esophageal squamous cell carcinoma
Oncotarget 9(33):23237-23252, 2018

211.
Ma Z, Taruno A, Ohmoto M, Jyotaki M, Lim JC, Miyazaki H, Niisato N, MARUNAKA Y, Lee RJ, Hoff H, Payne R, Demuro A, Parker l, Mitchell C, Henao-Mejia J, Tanis JE, Matsumoto I, Tordoff MG, Foskett JK.
CALHM3 is essential for rapid ion channel-mediated purinergic neurotransmission of GPCR-mediated tastes.
Neuron 98(3):547-561, 2018

210.
Kuwahara A, Kuwahara Y, Inui T, MARUNAKA Y.
Regulation of ion transport in the intestine by free fatty acid receptor 2 and 3: possible involvement of the diffuse chemosensory system.
Int J Mol Sci. 19:735, 2018

209.
Kogiso H, Ikeuchi Y, Sumiya M, Hosogi S, Tanaka S, Shimamoto C, Inui T, MARUNAKA Y, Nakahari T.
Seihai-to (TJ-90)-induced activation of airway ciliary beatings of mice: Ca2+ modulation of cAMP-Stimulated Ciliary Beatings via PDE1.
Int J Mol Sci. 19:658, 2018

208.
Ikeuchi Y, Kogiso H, Hosogi S, Tanaka S, Shimamoto C, Inui T, Nakahari T, MARUNAKA Y.
Measurement of [Cl]i unaffected by the cell volume change using MQAE-based two-photon microscopy in airway ciliary cells of mice.
J Physiol Sci. 68(2):191-199, 2018

207.
Matsumoto M, Zhang J, Zhang X, Liu J, Jiang JX, Yamaguchi K, Taruno A, Katsuyama M, Iwata K, Ibi M, Cui W, Matsuno K, MARUNAKA Y, Itoh Y, Torok NJ, Yabe-Nishimura C.
The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease.
Free Radic Biol Med 115:412-420, 2018

206.
Kogiso H, Hosogi S, Ikeuchi Y, Tanaka S, Inui T, MARUNAKA Y, Nakahari T.
[Ca2+]i modulation of cAMP-stimulated ciliary beat frequency via PDE1 in airway ciliary cells of mice.
Experimental Physiology 103(3):381-390, 2018

205.
Shiozaki A, Kudou M, Ichikawa D, Fujiwara H, Shimizu H, Ishimoto T, Arita T, Kosuga T, Konishi H, Komatsu S, Okamoto K, MARUNAKA Y, Otsuji E.
Esophageal cancer stem cells are suppressed by tranilast, a TRPV2 channel inhibitor.
J Gastroenterol 53(2):197-207, 2018

204.
MARUNAKA Y, Niisato N, Miyazaki H, Nakajima K, Taruno A, Sun H, Marunaka R, Okui M, Yamamoto T, Kanamura N, Kogiso H, Ikeuchi Y, Kashio M, Hosogi S, Nakahari T
Quercetin is a useful medicinal compound showing various actions including control of blood pressure, neurite elongation and epithelial ion transport
Current Med Chem 25:4876-4887, 2018

203.
Nomura T, Taruno A, Shiraishi M, Nakahari T, Inui T, Sokabe M, Eaton DC, MARUNAKA Y.
Current-direction/amplitude-dependent single channel gating kinetics of mouse pannexin 1 channel: a new concept for gating kinetics
Scientific Reports 7(1):10512, 2017

202.
MARUNAKA Y.
The mechanistic links between insulin and cystic fibrosis transmembrane conductance regulator (CFTR) Cl channel
Int J Mol Sci 18(8): pii: E1767, 2017

201.
Kosuga T, Shiozaki A, Kudou M, Yamazato Y, Ichikawa D, Komatsu S, Konishi K, Okamoto K, Shoda K, Arita T, Morimura R, Murayama Y, Kuriu Y, Ikoma H, Nakanishi M, Fujiwara H, MARUNAKA Y, Otsuji E.
Blockade of potassium ion transports enhances hypotonicity-induced cytocidal effects in gastric cancer
Oncotarget 8(60):101394-101405, 2017

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