和文総説
1) 細木誠之、池内優紀子、小木曽遥香、中張隆司、丸中良典.
Ambroxolによる線毛運動活性化機構〜細胞内pH・クロライドイオンを介して.
分子呼吸器病 20: 115-119, 2016
2) 新里直美、丸中良典
MAPKによるENaCを介するNa+再吸収制御機構
腎と透析 vol.80(3):423-425, 2016
3) 丸中良典
体液酸性化と漢方
phil漢方 62, 2016.10
4) 中張隆司、細木誠之、池内優紀子、小木曽遥香、丸中良典
去痰剤による気道線毛運動活性化とそのメカニズム
日本肺サーファクタント・界面医学会雑誌 第47巻、2016.10.28
和文その他
1)丸中良典
座談会:酸塩基平衡と生活習慣病
出席者)富野康日己、原茂子、丸中良典、阿部倫明、鶴岡秀一
腎・高血圧の最新治療 Vol.5 No.4 2016
英文総説
1) Ma Z, Tanis JE, Taruno A, Foskett JK.
Calcium homeostasis modulator (CALHM) ion channels.
Pflugers Arch 468(3):395-403, 2016.
2) Marunaka Y, Niisato N, Miyazaki H, Nakajima K, Taruno A, Sun H, Marunaka R, Okui M, Yamamoto T, Kanamura N, Kogiso H, Ikeuchi Y, Kashio M, Hosogi S, Nakahari T
Quercetin is a useful medicinal compound showing various actions including control of blood pressure, neurite elongation and epithelial ion transport
Current Med Chem 23:1-12, 2016
3) Marunaka Y, Marunaka R, Sun H, Yamamoto T, Kanamura N, Taruno A
Na+ homeostasis by epithelial Na+ channel (ENaC) and Nax channel (Nax): cooperation of ENaC and Nax
Annals of Translational Medicine 4 (Suppl 1):S11, 2016
原著
1) Tsuji T, Matsuo K, Nakahari T, Marunaka Y, Yokoyama T
Structural basis of the Inv compartment and ciliary abnormalities in inv/nphp2 mutant mice
Cytoskeleton 73:45-56, 2016
2) Pezzotti G, Bock RM, McEntire BJ, Jones E, Boffelli M, Zhu W, Baggio G, Boschetto F, Puppulin L, Adachi T, Yamamoto T, Kanamura N, Marunaka Y, Bal BS
Silicon nitride bioceramics induce chemically driven lysis in porphyromonas gingivalis.
Langmuir 32:3024-3035, 2016
3) Kimura T, Hashimoto Y, Tanaka M, Asano M, Yamazaki M, Oda Y, Toda H, Marunaka Y, Nakamura N, Fukui M
Sodium-chloride Difference and Metabolic Syndrome: A Population-based Large-scale Cohort Study
Internal Medicine 55(21):3085-3090, 2016
4) Tanaka S, Hosogi S, Sawabe Y, Shimamoto C, Matsumura H, Inui T, Marunaka Y,
Nakahari T
PPARα activation of NOS1 via PI3K/Akt in guinea pig antral mucous cells: NO-
enhancement in enhancement of Ca2+-regulated exocytosis
Biomed Res 37:167-178, 2016
5) Puppulin L, Miura Y, Casagrande E, Hasegawa M, Marunaka Y, Tone S, Sudo A, Pezzotti G
Validation of a protocol based on Raman and Infrared spectroscopies to nondestructively estimate the oxidative degradation of UHMWPE used in total joint arthroplasty.
Acta Biomaterialia 38:168-178, 2016
6) Kudou M, Shiozaki A, Kosuga T, IchikawaD, Konishi H, Morimura R, Komatsu S, Ikoma
H, Fujiwara H, Okamoto K, Hosogi S, Nakahari T, Marunaka Y, Otsuji E
Inhibition of Regulatory Volume Decrease Enhances the Cytocidal Effect of Hypotonic
Shock in Hepatocellular Carcinoma
J Cancer 7(11):1524-1533
7) Pezzotti G, McEntire BJ, BockR, Zhu W, Boschetto F, Rondinella A, Marin E, Marunaka Y, Adachi T, Yamamoto T, Kanamura N, Bal BS
In situ spectroscopic screening of osteosarcoma living cells on stoichiometry-modulated silicon nitride bioceramic surfaces
ACS Biomater Sci Eng 2 (7): 1121-1134, 2016
8) Nakajima K, Marunaka Y
Intracellular chloride ion concentration in differentiating neuronal cell and its role in growing neurite
Biochem Biophys Res Commun 14;479(2):338-342, 2016
国際学会 特別講演、招聘講演、基調講演、教育講演、シンポジウムなど
1)Marunaka Y.
How are Cl– and H+ involved in diseases such as hypertension, diabetes and cancer?
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
2)Taruno A, Marunaka Y. Purinergic neurotransmission of taste by CALHM channel.
17th ISOT JASTS 50th Annual Meeting. 2016.6. 5-9; Yokohama.
3) Marunaka Y. (基調講演)
How do chloride and hydrogen ions regulate body function?
2016 International Conference of Physiological Science. 2016.9.25-28; Beijing,China
4) Marunaka Y, Niisato N, Hongxin Sun, Inui T.
Insulin and the CFTR Chloride Channel. The 30th Annual North American Cystic Fibrosis Conference. 2016.10.27-29; Orlando, Florida, USA
5) Taruno A.
Molecular machinery for taste neurotransmission from the tongue to the brain. UK-Japan Frontiers of Science meeting 2016.11 6-9; Milton Keynes, UK
国際学会 一般講演(ポスター含む)
1) Taruno A, Sun H, Kashio M, Marunaka Y.
N-linked glycosylation regulates CALHM1 channel function and subcellular localization.
60th Annual Meeting of the Biophysical Society. 2016.2.27-3.2; Los Angeles, California.
2) Taruno A, Miyazaki H, Niisato N, Marunaka Y.
Homologous CALHM subunits assemble to form a novel voltage-gated ATP channel
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
3) Taruno A, Sun H, Kashio M, Marunaka Y.
Regulation of CALHM channels by N-linked glycosylation
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
4) Taruno A, Sun H, Marunaka Y.
Regulation of CALHM1 channel by protein S-palmitoylation
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
5) Kashio M, Taruno A, Marunaka Y.
Polarized sorting of CALHM channels in epithelial cells
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
6) Taruno A, Kashio M, Marunaka Y.
Gene targeting of the Calhm1 locus for functional analysis of CALHM1 channel in vivo
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
7) Taruno A, Kashio M, Sun H, Kobayashi K, Sano H, Nambu A, Marunaka Y.
Adeno-associated virus-mediated gene transfer into taste cells in vivo
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
8) Nomura T, Shiraishi M, Taruno A, Sokabe M, Marunaka Y.
Current-direction/amplitude-dependent single channel gating kinetics of Pannexin 1 channel
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
9) Sun H, Niisato N, Marunaka Y.
Insulin is involved in transcriptional regulation of NKCC and the CFTR Cl– channel through PI3K activation and ERK inactivation in renal epithelial cells
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
10) Ikeuch Y, Kogiso H, Tanaka S, Hosogi S, Nakahari T, Marunaka Y.
Activation of ciliary beating by carbocistein via modulation of [Cl–]i and pHi in bronchiolar ciliary cells in mice.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
11) Kogiso H, Hosogi S, Ikeuchi Y, Tanaka S, Shimamoto C, Nakahari T, Marunaka Y.
Ciliary beat frequency modulated by PDE1A activity in Procaterol stimulated mouse bronchiole.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
12) Miyazaki H, Ue T, Tanaka S, Nakayama Y, Marunaka Y.
The molecular mechanism of intracellular Cl- in cancer progression by regulating Src kinase signal cascades.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
13) Miyazaki H, Tanaka S, Marunaka Y.
The expression of Cl– transporter controls cell proliferation via changes in the cytosolic Cl– concentration in human gastric cancer cells.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
14) Hosogi S, Kogiso H, Ikeuchi Y, Nakahari T, Marunaka Y.
Ambroxol-stimulated increase in CBA and CBF via pHi increase and [Cl–] decrease in airway ciliary cells of mice.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
15) Nakajima K, Marunaka Y, Min Z.
KCNJ15/Kir4.2 and intracellular polyamines couples to sense weak extracellular electric field in electrotaxis.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
16) Tanaka S, Hosogi S, Shimamoto C, Matsumura H, Nakahari T, Marunaka Y.
PPARα-stimulated NOS1 phosphorylation mediated via PI3K/Akt in antral mucous cells: enhancement of Ca2+-regulated exocytosis
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
17) Puppulin Leonardo , Pezzotti Giuseppe, Hosogi S, Nakahari T, Marunaka Y.
New method based on Raman spectroscopy to detect in-situ concentration of HCO3–, Na+ and K+ from physiologically relevant solutions.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
18) Kuremoto T, Murakami K, Hosogi S, Yasuda M, Nakahari T, Marunaka Y.
Effect of IL-13 on the ciliary beating of nasal epithelium of mice.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
19) Sasamoto K, Niisato N, Marunaka Y.
Simulation of Cl– secretion in epithelial tissues: New methodology estimating activity of electroneutral Cl– transporter.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
20) Sumiya S, Hosogi S, Ikeuchi Y, Kogiso H, Nakahari T, Marunaka Y.
Activation of ciliary beating by Seihai-to in distal airway epithelial cells of mice.
International Symposium on Ion Channels, Transporters and Signal Transduction. 2016.5.21; Kyoto
21) Taruno A, Sun Hongxin, Kashio M, Marunaka Y.
Regulation of CALHM1 channel by protein S-palmitoylation.
17th ISOT JASTS 50th Annual Meeting. 2016.6. 5-9; Yokohama.
22) Kashio M, Taruno A, Sun Hongxin, Kobayashi K, Sano H, Nambu A, Marunaka Y. Adeno-associated virus-mediated gene transduction of taste cells in vivo.
17th ISOT JASTS 50th Annual Meeting. 2016.6. 5-9; Yokohama.
国内学会 特別講演
1)Marunaka Y.
Cl– and H+ as mediators of biofunction and biodysfunction in health and disease.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
国内学会シンポジウム、ワークショップ、パネルディスカッションなど
1) Tamiya N, Hosogi S, Takemura Y, Iwasaki Y, Takayama K, Nakahari T, Marunaka Y.
Procaterol-stimulated increases in ciliary bend amplitude and ciliary beat frequency in mouse bronchioles.
第1回 アジア・オセアニア呼吸機能イメージングワークショップ/第8回 呼吸機能イメージング研究会学術集会 2016.1.29-31
2) Sawa T, Yoshida T, Ishiguro T, Horiba A, Futamura Y, Hasegawa T, Nakahari T.
New developed motion imaging to evaluate the effects of bronchodilator on human bronchial ciliary movement using bronchoscopic sample.
第1回 アジア・オセアニア呼吸機能イメージングワークショップ/第8回 呼吸機能イメージング研究会学術集会 2016.1.29-31
3) 小木曽遥香、池内優紀子、細木 誠之、田中早織、島本史夫、中張隆司、丸中良典.
Procaterol 刺激時マウス末梢気道線毛のCa2+依存性PDE1Aによる周波数調節.
第11回京滋呼吸器リサーチフォーラム 2016.3.19; 京都
4) Taruno A, Miyazaki H, Niisato N, Sun H, Kashio M, Marunaka Y
CALHM1 and CALHM3 are assembled to form a novel voltage-gated ATP channel.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
5) Puppulin L, Pezzotti G, Hosogi S, Nakahari T, Marunaka Y
New method based on Raman spectroscopy to detect in-situ concentration of HCO3-, Na+ and K+ from physiological relevant solutions.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
6) Pezzotti Giuseppe, Ikegaya H, Miyamori D, Tamamoto T, Kanamura M, Adachi T, Sugano N, Zhu Wenliang, Takahashi Y, Yamamoto K, Puppulin Leonardo, Marunaka Y
The role of Raman spectroscopy in preventive medicine.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
7) 丸中良典.
ブラジル産プロポリスの糖尿病に対する効果
第16回日本抗加齢医学会総会. 2016.6.10-12; 横浜
8) Taruno A, Miyazaki H, Niisato N, Hongxin K, Kashio M, Marunaka Y.
Homologous CALHM subunits assemble to form a novel voltage-gated ATP channel
The 39th Annual Meeting of the Japan Neuroscience Society.. 2016.7.20-22; 横浜
国内学会 一般講演(ポスター含む)
1) 角谷昌子、小木曽遥香、細木誠之、中張隆司、丸中良典.
清肺湯(TJ-90)の有する気道線毛運動活性化効果
京都漢方医学研究会. 2016.1.30. 京都
2) Kashio M, Taruno A, Sun Hongxin, Kobayashi K, Sano H, Ohsaki Y, Kido M, Nambu A, Marunaka Y
Analyses of subcellular localization of CALHM1 channel.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
3) Ikeuch Y, Kogiso H, Tanaka S, Hosogi S, Nakahari T, Marunaka Y
Activation of ciliary beating by carbocistein via modulation of [Cl–]i and pHi in bronchiolar ciliary cells in mice.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
4) Kogiso H, Hosogi S, Ikeuchi Y, Tanaka S, Shimamoto C, Nakahari T, Marunaka Y
Ciliary beat frequency modulated by PDE1A activity in procaterol stimulated mouse bronchiole.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
5) Kuremoto T, Murakami K, Hosogi S, Yasuda M, Nakahari T, Marunaka Y
Effect of IL-13 on the ciliary beating of nasal epithelium of mice.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
6) Sumiya S, Hosogi S, Ikeuchi Y, Kogiso H, Nakahari T, Marunaka Y
Activation of ciliary beating by Seihai-to in distal airway epithelial cells of mice.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
7) Sasamoto K, Niisato N, Marunaka Y
Simulation of Cl– secretion in epithelial tissues: New methodology estimating activity of electroneutral Cl– transporter.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
8) Niisato N, Marunaka Y
A regulatory mechanism for apical surface expression of ENaC through the ubiquitin-proteasome pathway in renal epithelial A6 cells.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
9) Nakajima K, Marunaka Y, Zhao Min.
KCNJ15/Kir4.2 and intracellular polyamines ouples to sense weak extracellular electric field in electrotaxis.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
10) Tanaka S, Hosogi S, Shimamoto C, Matsumura H, Nakahari T, Marunaka Y
PPARα-stimulated NOS1 phosphorylation mediated via PI3K/Akt in antral mucous cells: enhancement of Ca2+-regulated exocytosis.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
11) Hosogi S, Kogiso H, Ikeuchi Y, Nakahari T, Marunaka Y
Ambroxol-stimulated increase in CBA and CBF via pHi increase and [Cl–] decrease in airway ciliary cells of mice.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
12) Miyazaki H, Ue T, Tanaka S, Nakayama Y, Marunaka Y
The molecular mechanism of intracellular Cl– in cancer progression by regulating Src kinase signal cascades.
The 93rd Annual Meeting of the Physiological Society of Japan. 2016.3.22-24; Sapporo.
13) 樽野陽幸、孫紅昕 、加塩麻紀子、丸中良典.
S-パルミトイル化修飾によるCALHM1チャネル機能制御
日本膜学会38年会 2016.5.10.10-11; 東京
14) 中島謙一、丸中良典、Min Zhao.
電気走性electrotaxis におけるK+ channel KCNJ15/kir4.2と細胞内ポリアミンの役割
日本膜学会38年会 2016.5.10.10-11; 東京
15) 宮崎裕明、田中幸恵、丸中良典.
膜輸送体の発現変化に伴った細胞内Cl–濃度変化が胃癌細胞増殖を制御する
日本膜学会38年会 2016.5.10.10-11; 東京
16) 小木曾遥香、池内優紀子、細木誠之、田中早織、島本史夫、中張隆司、丸中良典.
マウス末梢気道線毛運動周波数のcAMP調節:Ca2+依存性PDE1Aの役割.
第15回肺サーファクタント分子病態研究会. 2016.6.4; 札幌
学術集会でのプロシーディングス
1) Marunaka Y.
Cl- and H+ as mediators of biofunction and biodysfunction in health and disease.
J Physiol Sci. 66 (suppl-1): 4, 2016.
2) Kashio M, Taruno A, Sun Hongxin, Kobayashi K, Sano H, Ohsaki Y, Kido M, Nambu A, Marunaka Y
Analyses of subcellular localization of CALHM1 channel.
J Physiol Sci. 66 (suppl-1): 10, 2016.
3) Pezzotti Giuseppe, Ikegaya H, Miyamori D, Tamamoto T, Kanamura M, Adachi T, Sugano N, Zhu Wenliang, Takahashi Y, Yamamoto K, Puppulin Leonardo, Marunaka Y
The role of Raman spectroscopy in preventive medicine.
J Physiol Sci. 66 (suppl-1): 38, 2016.
4) Puppulin L, Pezzotti G, Hosogi S, Nakahari T, Marunaka Y
New method based on Raman spectroscopy to detect in-situ concentration of HCO3-, Na+ and K+ from physiological relevant solutions.
J Physiol Sci. 66 (suppl-1): 38, 2016.
5) Taruno A, Miyazaki H, Niisato N, Sun H, Kashio M, Marunaka Y
CALHM1 and CALHM3 are assembled to form a novel voltage-gated ATP channel.
J Physiol Sci. 66 (suppl-1): 39, 2016.
6) Ikeuch Y, Kogiso H, Tanaka S, Hosogi S, Nakahari T, Marunaka Y
Activation of ciliary beating by carbocistein via modulation of [Cl–]i and pHi in bronchiolar ciliary cells in mice.
J Physiol Sci. 66 (suppl-1): 86, 2016.
7) Kogiso H, Hosogi S, Ikeuchi Y, Tanaka S, Shimamoto C, Nakahari T, Marunaka Y
Ciliary beat frequency modulated by PDE1A activity in procaterol stimulated mouse bronchiole.
J Physiol Sci. 66 (suppl-1): 86, 2016.
8) Kuremoto T, Murakami K, Hosogi S, Yasuda M, Nakahari T, Marunaka Y
Effect of IL-13 on the ciliary beating of nasal epithelium of mice.
J Physiol Sci. 66 (suppl-1): 86, 2016.
9) Sumiya S, Hosogi S, Ikeuchi Y, Kogiso H, Nakahari T, Marunaka Y
Activation of ciliary beating by Seihai-to in distal airway epithelial cells of mice.
J Physiol Sci. 66 (suppl-1): 87, 2016.
10) Sasamoto K, Niisato N, Marunaka Y
Simulation of Cl– secretion in epithelial tissues: New methodology estimating activity of electroneutral Cl– transporter.
J Physiol Sci. 66 (suppl-1): 89, 2016.
11) Niisato N, Marunaka Y
A regulatory mechanism for apical surface expression of ENaC through the ubiquitin-proteasome pathway in renal epithelial A6 cells.
J Physiol Sci. 66 (suppl-1): 141, 2016.
12) Nakajima K, Marunaka Y, Zhao Min.
KCNJ15/Kir4.2 and intracellular polyamines ouples to sense weak extracellular electric field in electrotaxis.
J Physiol Sci. 66 (suppl-1): 143, 2016.
13) Tanaka S, Hosogi S, Shimamoto C, Matsumura H, Nakahari T, Marunaka Y
PPARα-stimulated NOS1 phosphorylation mediated via PI3K/Akt in antral mucous cells: enhancement of Ca2+-regulated exocytosis.
J Physiol Sci. 66 (suppl-1): 144, 2016.
14) Hosogi S, Kogiso H, Ikeuchi Y, Nakahari T, Marunaka Y
Ambroxol-stimulated increase in CBA and CBF via pHi increase and [Cl–] decrease in airway ciliary cells of mice.
J Physiol Sci. 66 (suppl-1): 159, 2016.
15) Miyazaki H, Ue T, Tanaka S, Nakayama Y, Marunaka Y
The molecular mechanism of intracellular Cl- in cancer progression by regulating Src kinase signal cascades.
J Physiol Sci. 66 (suppl-1): 159, 2016.
16) 樽野陽幸、孫紅昕 、加塩麻紀子、丸中良典.
S-パルミトイル化修飾によるCALHM1チャネル機能制御
膜 ; 日本膜学会38年会; 講演要旨集. P48, 2016
17) 中島謙一、丸中良典、Min Zhao.
電気走性electrotaxis におけるK+ channel KCNJ15/kir4.2と細胞内ポリアミンの役割
膜 ; 日本膜学会38年会; 講演要旨集. P49, 2016
18) 宮崎裕明、田中幸恵、丸中良典.
膜輸送体の発現変化に伴った細胞内Cl–濃度変化が胃癌細胞増殖を制御する
膜 ; 日本膜学会38年会; 講演要旨集. P51, 2016
19) 丸中良典.
ブラジル産プロポリスの糖尿病に対する効果
第16回日本抗加齢医学会総会 (プログラム・抄録集); P256, 2016
科研費
1) 丸中良典(研究代表者):挑戦的萌芽研究 (継続、H27~H28) 「MRI・ラマン分光による間質液pH・重炭酸イオン濃度の非侵襲的測定法開発」
2)宮崎裕明(研究代表者):基盤研究(C)(一般)新規、H28~H30)「「癌細胞のクロライドシフト」による細胞接着能変化を介した癌転移メカニズムの解明」
3)樽野陽幸(研究代表者):若手研究(A)(継続、H26~H28年度)「味覚情報の抽出・処理・統合機構の解析」
4) 樽野陽幸(研究代表者):挑戦的萌芽研究 (新規、H28~H30)「CALHMチャネル機能を基盤とした感覚情報伝達機構の新規概念の構築」
5)細木誠之(研究代表者):基盤研究(C)(一般)(継続、H26~H28)「癌幹細胞特異的プロトン制
御機構を分子標的とした新たな癌治療戦略の展開」
6) 中島謙一(研究代表者):基盤研究(C)(一般)新規、H28~H30)「細胞内クロライドイオンによ
る電気走性時の細胞極性の形成メカニズム」
7) 加塩麻紀子(研究代表者):若手研究(B)(一般)(継続、H27~H28)「ヘテロメリックCALHM1/CALHM3チャネルによる味覚神経伝達」
8) 孫 紅昕 (研究代表者):若手研究(B)(一般)(新規、H28~H30) 「味蕾における塩味コーディング様式の解明」
9) プップリン レオナルド(研究代表者):若手研究(B)(一般)
(新規、H28~H30) 「光学的方法を用いた組織間質液イオン環境の非侵襲的測定法開発」
10) 新里直美(研究代表者):基盤研究(C)(一般)継続、H27~H29)「形質膜タンパク質のプロテアソームへの新規ターゲティング機構の解明」
民間研究財団
1) 加塩麻紀子(研究代表者) ソルトサイエンス研究財団 平成28年度研究助成
「味蕾における塩味受容の細胞基盤の解明」
受賞
加塩麻紀子
日本生理学会 入澤宏・彩記念若手研究奨励賞
「CALHM1チャネルの細胞内局在解析」
池内優紀子
Activation of ciliary beating by carbocistein via modulation of [Cl-]i and pHi in bronchiolar ciliary cells in mice
第93回日本生理学会大会「学生ポスター優秀賞」
小木曽遥香
Ciliary beat frequency modulated by PDE1A activity in procaterol stimulated mouse bronchiole
第93回日本生理学会大会「学生ポスター優秀賞」
笹本浩平(学部学生)
京都府立医科大学 青蓮会 研究奨励賞
Simulation of Cl– secretion in epithelial tissues: New methodology estimating activity of electro-neutral Cl– transporter